A novel cardioprotective p38-MAPK/mTOR pathway
Posted: Fri Oct 21, 2011 9:49 amMAP Kinase Resource Forum
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p38 MAPK-related papers
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Posted: Fri Oct 21, 2011 9:49 amRe: A novel cardioprotective p38-MAPK/mTOR pathway.
Posted: Fri Oct 21, 2011 10:09 amnice one!!!
p38 MAPK-related papers
Posted: Fri Jun 01, 2012 2:54 amPut all p38 MAPK-related papers here, please
Re: p38 MAPK-related papers
Posted: Fri Jun 01, 2012 3:01 amRoles of p38 MAPKs in invasion and metastasis
Biochem Soc Trans. 2012 Feb;40(1):79-84
del Barco Barrantes I, Nebreda AR
Institute for Research in Biomedicine (IRB Barcelona), Baldiri Reixac 10, 08028 Barcelona, Spain. ivan.delbarco@irbbarcelona.org
Abstract
Cells from primary tumours need to go through several steps to become fully metastatic. During this process, cancer cells acquire the ability to invade, migrate across the surrounding tissue, enter into the circulation and colonize distant organs. In the present paper, we review recent progress in understanding how the p38 MAPK (mitogen-activated protein kinase) signalling pathway participates in the different steps of metastasis. Experimental evidence suggests that tumour cells need to modulate p38 MAPK activity levels to successfully metastasize.
Pubmed link: http://www.ncbi.nlm.nih.gov/pubmed/22260669
Biochem Soc Trans. 2012 Feb;40(1):79-84
del Barco Barrantes I, Nebreda AR
Institute for Research in Biomedicine (IRB Barcelona), Baldiri Reixac 10, 08028 Barcelona, Spain. ivan.delbarco@irbbarcelona.org
Abstract
Cells from primary tumours need to go through several steps to become fully metastatic. During this process, cancer cells acquire the ability to invade, migrate across the surrounding tissue, enter into the circulation and colonize distant organs. In the present paper, we review recent progress in understanding how the p38 MAPK (mitogen-activated protein kinase) signalling pathway participates in the different steps of metastasis. Experimental evidence suggests that tumour cells need to modulate p38 MAPK activity levels to successfully metastasize.
Pubmed link: http://www.ncbi.nlm.nih.gov/pubmed/22260669